PANCREAZE is indicated for the treatment of exocrine pancreatic insufficiency in adult and pediatric patients.

When Your Patients' Mealtimes Seem Like a Gamble, EAZE Their EPI Symptoms With PANCREAZE.

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PANCREAZE is clinically proven to improve symptoms of Exocrine Pancreatic Insufficiency (EPI), such as abdominal pain, bloating, diarrhea, and greasy stools.1 It is the only pancreatic enzyme replacement therapy capsule that does not use phthalates as an additive in its formulation.2

The enzymes in PANCREAZE help the body digest food properly and absorb fat, protein, and carbohydrates — which are needed for healthy growth, weight gain, and improved nutritional health.

Learn More About Pancreaze →
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Supporting Patients With EPI: How PANCREAZE Can Help

Watch the video to learn more about how to support your patients with EPI.

According To The American Gastroenterological Association (AGA), EPI Is Frequently Underdiagnosed.

If your patient presents with one or more symptoms of abdominal pain, flatulence, steatorrhea, diarrhea, or unexplained weight loss, consider testing for EPI.

Abdominal Pain Symptom
Abdominal Pain
Flatulence Symptom
Flatulence
Steatorrhea Symptom
Steatorrhea
Diarrhea Symptom
Diarrhea
Weight Loss Symptom
Weight Loss
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A Trusted Enzyme Replacement Therapy For Over 15 Years Is Right For You.

PANCREAZE is clinically proven to improve symptoms of EPI and to improve fat and protein absorption

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Flexible Dosing.

All 6 doses of PANCREAZE use a phthalate-free formulation, including the 37,000 lipase unit dose.3 This can be a convenient, appropriate dose for many EPI patients — minimizing the number of capsules they take daily.

6 Available Strengths (Lipase Units)
2600 Dose

2,600

4200 Dose

4,200

10500 Dose

10,500

16800 Dose

16,800

21000 Dose

21,000

37000 Dose

37,000

Find the right dose for your patient.

Use our Dosing Calculator - a simple tool to help guide individualized dosing.

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PANCREAZE Is A Preferred Brand On Multiple Insurance Plans & Covered On 81% Of Commercial Insurance Plans.

Eligible patients may pay as little as $0 on their co-pay with the PANCREAZE Savings Card.*

Save up to $2,000 per prescription fill with a maximum yearly benefit of $3,500.*

Pancreaze Savings Card Learn more about savings →

PANCREAZE is preferred for Cigna HealthcareSM Commercial Formularies

For patients not on Cigna plans, use our online Insurance Coverage Lookup and Patient Savings Tool to check their coverage.

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Help Your Patients Turn Mealtimes From Chance To Consistency With PANCREAZE.

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Pancreaze Capsule

† Source: Managed Markets Insight & Technology, LLC, database as of January 2026. Certain plans may require prior authorization.

‡ This is not a guarantee of coverage or payment (partial or full). Actual benefits are determined by each plan administrator in accordance with its respective policy and procedures. Nothing herein may be construed as an endorsement, approval, recommendation, representation or warranty of any kind by any plan or insurer referenced herein.

*Patient Co-Pay Eligibility, Terms, and Conditions

Eligible patients may pay a minimum of $0 and receive up to $2,000 off the patient's co-pay or out-of-pocket expenses per prescription fill of PANCREAZE (pancrelipase) capsules with a maximum yearly benefit of $3,500. Out-of-pocket expenses may vary. Patient Instructions: In order to redeem the offer, you must have a valid prescription for PANCREAZE. This offer may not be redeemed for cash. By using this offer, you are certifying that you meet the eligibility criteria and will comply with the terms and conditions below. Terms and conditions: Offer is not transferable. Patients are not eligible if they are covered in whole or in part by any state program or federal healthcare program, including, but not limited to, Medicare or Medicaid (including Medicaid managed care), Medigap, VA, DOD, or TRICARE. Only valid in the United States, Puerto Rico, Guam and the U.S. Virgin Islands. Offer void where prohibited by law, taxed, or restricted. Other restrictions may apply. This program is not health insurance. VIVUS LLC has the right to rescind, revoke, or amend this program at any time without notice. Your participation in this program confirms that this offer is consistent with your insurance coverage and that you will report the value received if required by your insurance provider. When you use this card, you are certifying that you understand and will comply with the program rules, terms, and conditions.

Indication

PANCREAZE is indicated for the treatment of exocrine pancreatic insufficiency in adult and pediatric patients.

Important Safety Information

Fibrosing Colonopathy: Associated with high doses, usually over prolonged use and in pediatric patients with cystic fibrosis. Colonic stricture reported in pediatric patients less than 12 years of age with dosages exceeding 6,000 lipase units/kg/meal. Monitor during treatment for progression of preexisting disease. Do not exceed the recommended dosage, unless clinically indicated.

Hyperuricemia has been reported with high dosages; consider monitoring blood uric acid levels in patients with gout, renal impairment, or hyperuricemia.

Irritation of the oral mucosa may occur due to loss of protective enteric coating on the capsule contents.

The presence of porcine viruses that might infect humans cannot be definitely excluded.

Monitor patients with known reactions to proteins of porcine origin. If symptoms occur, initiate appropriate medical management; consider the risks and benefits of continued treatment.

Please read the PANCREAZE Medication Guide and PANCREAZE Product Information and discuss any questions you have with your doctor.

References: 1. References: Trapnell BC, Strausbaugh SD, Woo MS, et al. Efficacy and safety of PANCREAZE for treatment of exocrine pancreatic insufficiency due to cystic fibrosis. J Cyst Fibros. 2011;10(5):350-356. 2. Cystic Fibrosis Foundation. (n.d.). Phthalates. Retrieved from https://www.cff.org/phthalates. 3. PANCREAZE Full Prescribing Information. Campbell, CA: VIVUS LLC; 2024.